Pharmacokinetics of [14C]Abacavir, a Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase Inhibitor, Administered in a Single Oral Dose to HIV-1-Infected Adults: a Mass Balance Study
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| Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 1999-12, Vol.43 (12), p.2855-2861 |
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| container_title | Antimicrobial Agents and Chemotherapy |
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| creator | MCDOWELL, J. A CHITTICK, G. E RAVITCH, J. R POLK, R. E KERKERING, T. M STEIN, D. S |
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| doi_str_mv | 10.1128/aac.43.12.2855 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/aac.43.12.2855</identifier><identifier>PMID: 10582871</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>5'-Carboxylate ; 5'-Glucuronide ; Abacavir ; Adult ; Anti-HIV Agents ; Anti-HIV Agents - administration & dosage ; Anti-HIV Agents - cerebrospinal fluid ; Anti-HIV Agents - pharmacokinetics ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Biological and medical sciences ; Chromatography, High Pressure Liquid ; Dideoxynucleosides ; Dideoxynucleosides - administration & dosage ; Dideoxynucleosides - cerebrospinal fluid ; Dideoxynucleosides - pharmacokinetics ; Feces - chemistry ; HIV Infections ; HIV Infections - metabolism ; HIV Reverse Transcriptase ; HIV Reverse Transcriptase - antagonists & inhibitors ; HIV-1 ; Human immunodeficiency virus 1 ; Humans ; Male ; Medical sciences ; Middle Aged ; Pharmacology. Drug treatments ; Reverse Transcriptase Inhibitors ; Reverse Transcriptase Inhibitors - administration & dosage ; Reverse Transcriptase Inhibitors - cerebrospinal fluid ; Reverse Transcriptase Inhibitors - pharmacokinetics ; Spectrophotometry, Ultraviolet</subject><ispartof>Antimicrobial Agents and Chemotherapy, 1999-12, Vol.43 (12), p.2855-2861</ispartof><rights>2000 INIST-CNRS</rights><rights>Copyright © 1999 American Society for Microbiology</rights><rights>Copyright © 1999, American Society for Microbiology 1999</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a573t-416b251c5303c77f1908be52620ed93d88ec15482ead79741b7f8086e85ae203</citedby><cites>FETCH-LOGICAL-a573t-416b251c5303c77f1908be52620ed93d88ec15482ead79741b7f8086e85ae203</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC89576/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC89576/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1228096$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10582871$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MCDOWELL, J. A</creatorcontrib><creatorcontrib>CHITTICK, G. E</creatorcontrib><creatorcontrib>RAVITCH, J. R</creatorcontrib><creatorcontrib>POLK, R. E</creatorcontrib><creatorcontrib>KERKERING, T. M</creatorcontrib><creatorcontrib>STEIN, D. S</creatorcontrib><title>Pharmacokinetics of [14C]Abacavir, a Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase Inhibitor, Administered in a Single Oral Dose to HIV-1-Infected Adults: a Mass Balance Study</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob. Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>5'-Carboxylate</subject><subject>5'-Glucuronide</subject><subject>Abacavir</subject><subject>Adult</subject><subject>Anti-HIV Agents</subject><subject>Anti-HIV Agents - administration & dosage</subject><subject>Anti-HIV Agents - cerebrospinal fluid</subject><subject>Anti-HIV Agents - pharmacokinetics</subject><subject>Antibiotics. Antiinfectious agents. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>10582871</pmid><doi>10.1128/aac.43.12.2855</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0066-4804 |
| ispartof | Antimicrobial Agents and Chemotherapy, 1999-12, Vol.43 (12), p.2855-2861 |
| issn | 0066-4804 1098-6596 |
| language | eng |
| recordid | cdi_highwire_asm_aac_43_12_2855 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | 5'-Carboxylate 5'-Glucuronide Abacavir Adult Anti-HIV Agents Anti-HIV Agents - administration & dosage Anti-HIV Agents - cerebrospinal fluid Anti-HIV Agents - pharmacokinetics Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Biological and medical sciences Chromatography, High Pressure Liquid Dideoxynucleosides Dideoxynucleosides - administration & dosage Dideoxynucleosides - cerebrospinal fluid Dideoxynucleosides - pharmacokinetics Feces - chemistry HIV Infections HIV Infections - metabolism HIV Reverse Transcriptase HIV Reverse Transcriptase - antagonists & inhibitors HIV-1 Human immunodeficiency virus 1 Humans Male Medical sciences Middle Aged Pharmacology. Drug treatments Reverse Transcriptase Inhibitors Reverse Transcriptase Inhibitors - administration & dosage Reverse Transcriptase Inhibitors - cerebrospinal fluid Reverse Transcriptase Inhibitors - pharmacokinetics Spectrophotometry, Ultraviolet |
| title | Pharmacokinetics of [14C]Abacavir, a Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase Inhibitor, Administered in a Single Oral Dose to HIV-1-Infected Adults: a Mass Balance Study |
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