Organoids and organ-on-chip technology for investigating host-microorganism interactions

Recent advances in organoid and organ-on-chip (OoC) technologies offer an unprecedented level of tissue mimicry. These models can recapitulate the diversity of cellular composition, 3D organization, and mechanical stimulation. These approaches are intensively used to understand complex diseases. Thi...

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Veröffentlicht in:	Microbes and infection 2024-09, Vol.26 (7), p.105319, Article 105319
Hauptverfasser:	Walocha, Remigiusz, Kim, MinHee, Wong-Ng, Jérôme, Gobaa, Samy, Sauvonnet, Nathalie
Format:	Artikel
Sprache:	eng
Schlagworte:	Host-pathogen interaction Infection Life Sciences Microphysiological Organ-on-a-chip Organoid Tissue mechanics
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Recent advances in organoid and organ-on-chip (OoC) technologies offer an unprecedented level of tissue mimicry. These models can recapitulate the diversity of cellular composition, 3D organization, and mechanical stimulation. These approaches are intensively used to understand complex diseases. This review focuses on the latest advances in this field to study host-microorganism interactions.
ISSN:	1286-4579 1769-714X 1769-714X
DOI:	10.1016/j.micinf.2024.105319