Comprehensive allelotyping of human hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common cancers in many parts of the world, however the molecular mechanisms underlying liver cell transformation remain obscure. A genome-wide scan of loss of heterozygosity (LOH) in tumors provides a powerful tool to search for genes involved in neo...

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Veröffentlicht in:	Oncogene 1997-06, Vol.14 (24), p.2927-2933
Hauptverfasser:	NAGAI, H, PINEAU, P, TIOLLAIS, P, BUENDIA, M. A, DEJEAN, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biological and medical sciences Carcinoma, Hepatocellular Carcinoma, Hepatocellular - genetics Chromosome 1 Chromosome 8 Chromosomes, Human DNA, Neoplasm DNA, Neoplasm - genetics DNA, Satellite DNA, Satellite - genetics Gastroenterology. Liver. Pancreas. Abdomen Gene Deletion Genetic markers Genetic transformation Genome, Human Genomes Hepatitis B Hepatocellular carcinoma Hepatocytes Heterozygosity Heterozygote Humans Life Sciences Liver cancer Liver Neoplasms Liver Neoplasms - genetics Liver. Biliary tract. Portal circulation. Exocrine pancreas Loss of heterozygosity Medical sciences Microsatellites Molecular modelling Polymerase Chain Reaction Polymorphism, Genetic Tumors
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