PknB kinase activity is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phospho‐Ser/Thr phosphatase, in Mycobacterium tuberculosis

Summary Bacterial genomics revealed the widespread presence of eukaryotic‐like protein kinases and phosphatases in prokaryotes, but little is known on their biochemical properties, regulation mechanisms and physiological roles. Here we focus on the catalytic domains of two trans‐membrane enzymes, th...

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Veröffentlicht in:Molecular microbiology 2003-09, Vol.49 (6), p.1493-1508
Hauptverfasser: Boitel, Brigitte, Ortiz‐Lombardía, Miguel, Durán, Rosario, Pompeo, Fréderique, Cole, Stewart T., Cerveñansky, Carlos, Alzari, Pedro M.
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Sprache:eng
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