Prevalence of Common HFE and SERPINA1 Mutations in Patients with Hepatocellular Carcinoma in a Moroccan Population

Background Hereditary hemochromatosis and SERPINA1 mutation were reported to affect liver functions. Our objective was to estimate the prevalence of HFE and SERPINA1 (formerly known as α1-antitrypsin, AAT) mutations and assess their influence on hepatocellular carcinoma development. Methods This stu...

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Veröffentlicht in:	Archives of medical research 2008-02, Vol.39 (2), p.236-241
Hauptverfasser:	Ezzikouri, Sayeh, El Feydi, Abdellah Essaid, El Kihal, Latifa, Afifi, Rajae, Benazzouz, Mustapha, Hassar, Mohammed, Chafik, Abdelaziz, Pineau, Pascal, Benjelloun, Soumaya
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alleles alpha 1-Antitrypsin - genetics Arabs Cancer Carcinoma, Hepatocellular - epidemiology Carcinoma, Hepatocellular - genetics Female Genetic Predisposition to Disease - genetics Genetics Hemochromatosis Protein Hepatocellular carcinoma Heterozygote HFE mutations Histocompatibility Antigens Class I - genetics Homozygote Human genetics Human health and pathology Humans Hépatology and Gastroenterology Internal Medicine Life Sciences Liver Neoplasms - epidemiology Liver Neoplasms - genetics Male Membrane Proteins - genetics Middle Aged Morocco Mutation, Missense Prevalence Retrospective Studies S mutation Z mutation
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