Targeting membrane trafficking in infection prophylaxis: dynamin inhibitors

Many pathogens hijack existing endocytic trafficking pathways to exert toxic effects in cells. Dynamin controls various steps of the intoxication process used by numerous pathogenic bacteria, viruses, and toxins. Targeting dynamin with pharmaceutical compounds may therefore have prophylactic potenti...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Trends in cell biology 2013-02, Vol.23 (2), p.90-101
Hauptverfasser:	Harper, Callista B, Popoff, Michel R, McCluskey, Adam, Robinson, Phillip J, Meunier, Frédéric A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylamides - pharmacology Animals Bacterial Infections - drug therapy Candidiasis - drug therapy Cell Line, Tumor Clathrin-Coated Vesicles - drug effects Clathrin-Coated Vesicles - microbiology dynamin Dynamins - antagonists & inhibitors Dynamins - metabolism endocytosis Endocytosis - drug effects Enzyme Inhibitors - pharmacology Humans Hydrazones - pharmacology Indoles - pharmacology Life Sciences Microbial Sensitivity Tests Naphthols - pharmacology neurotoxins pathogens Pathology prophylaxis Protein Transport - drug effects Shiga Toxin - antagonists & inhibitors Toxicology trafficking Virus Internalization - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!