The emerging role of SHANK genes in neuropsychiatric disorders

ABSTRACT The genetic heterogeneity of neuropsychiatric disorders is high, but some pathways emerged, notably synaptic functioning. A large number of mutations have been described in genes such as neuroligins, neurexins, and SHANK that play a role in the formation and the maintenance of synapses. Thi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Developmental neurobiology (Hoboken, N.J.) N.J.), 2014-02, Vol.74 (2), p.113-122
Hauptverfasser:	Guilmatre, Audrey, Huguet, Guillaume, Delorme, Richard, Bourgeron, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease Alzheimer Disease - genetics Alzheimer Disease - physiopathology Animals Bipolar Disorder Bipolar Disorder - genetics Bipolar Disorder - physiopathology Child Development Disorders, Pervasive Child Development Disorders, Pervasive - genetics Child Development Disorders, Pervasive - physiopathology Chromosome Deletion Chromosome Disorders Chromosome Disorders - genetics Chromosome Disorders - physiopathology Chromosomes, Human, Pair 22 Chromosomes, Human, Pair 22 - genetics Cognitive science Human health and pathology Humans Life Sciences Mental Disorders Mental Disorders - genetics Mental Disorders - physiopathology Mutation Nerve Tissue Proteins Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism neuropsychiatric disorders Phelan‐McDermid syndrome Psychiatrics and mental health Schizophrenia Schizophrenia - genetics Schizophrenia - physiopathology SHANK
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!