Lebecin, a new C-type lectin like protein from Macrovipera lebetina venom with anti-tumor activity against the breast cancer cell line MDA-MB231

C-type lectins like proteins display various biological activities and are known to affect especially platelet aggregation. Few of them have been reported to have anti-tumor effects. In this study, we have identified and characterized a new C-type lectin like protein, named lebecin. Lebecin is a het...

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Veröffentlicht in:	Toxicon (Oxford) 2014-08, Vol.86, p.16-27
Hauptverfasser:	Jebali, Jed, Fakhfekh, Emna, Morgen, Maram, Srairi-Abid, Najet, Majdoub, Hafedh, Gargouri, Ali, El Ayeb, Mohamed, Luis, José, Marrakchi, Naziha, Sarray, Sameh
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglomeration Amino Acid Sequence Amino acids Animals Base Sequence Breast Breast Neoplasms - pathology Cancer Cell adhesion Cell Adhesion - drug effects Cell Line, Tumor Cell migration Cell Movement - drug effects Cell Proliferation - drug effects Cellular Biology Cloning, Molecular Female Humans Inhibitors Lectins Lectins, C-Type - chemistry Lectins, C-Type - isolation & purification Life Sciences Models, Molecular Molecular cloning Molecular modeling Molecular Sequence Data Peptides Protein Structure, Tertiary Proteins Sequence Alignment Sequence Analysis, Protein Snake venom Viper Venoms - chemistry Viper Venoms - isolation & purification Viper Venoms - pharmacology Viperidae
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