Tyrosinase and Layer-by-Layer supported tyrosinases in the synthesis of lipophilic catechols with antiinfluenza activity

Catechol derivatives with lipophilic properties have been selectively synthesized by tyrosinase in high yield avoiding long and tedious protection/deprotection steps usually required in traditional procedures. The synthesis was effective also with immobilized tyrosinase able to perform for more runs...

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Veröffentlicht in:Bioorganic & medicinal chemistry 2013-12, Vol.21 (24), p.7699-7708
Hauptverfasser: Bozzini, Tiziana, Botta, Giorgia, Delfino, Michela, Onofri, Silvano, Saladino, Raffaele, Amatore, Donatella, Sgarbanti, Rossella, Nencioni, Lucia, Palamara, Anna Teresa
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Sprache:eng
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