Revisiting the regiospecificity of Burkholderia xenovorans LB400 biphenyl dioxygenase toward 2,2'-dichlorobiphenyl and 2,3,2',3'-tetrachlorobiphenyl

2,2'-Dichlorobiphenyl (CB) is transformed by the biphenyl dioxygenase of Burkholderia xenovorans LB400 (LB400 BPDO) into two metabolites (1 and 2). The most abundant metabolite, 1, was previously identified as 2,3-dihydroxy-2'-chlorobiphenyl and was presumed to originate from the initial a...

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Veröffentlicht in:The Journal of biological chemistry 2004-11, Vol.279 (46), p.47489-47496
Hauptverfasser: Barriault, Diane, Lépine, François, Mohammadi, Mahmood, Milot, Sylvain, Leberre, Nicolas, Sylvestre, Michel
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Sprache:eng
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