Cloning, localization and differential expression of the Trypanosoma cruzi TcOGNT-2 glycosyl transferase

The surface of Trypanosoma cruzi is covered by a dense glycocalix which is characteristic of each stage of the life cycle. Its composition and complexity depend mainly on mucin-like proteins. A remarkable feature of O-glycan biosynthesis in trypanosomes is that it initiates with the addition of a Gl...

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Veröffentlicht in:	Gene 2012-05, Vol.498 (2), p.147-154
Hauptverfasser:	Chiribao, María Laura, Libisch, María Gabriela, Osinaga, Eduardo, Parodi-Talice, Adriana, Robello, Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Acetylglucosamine - metabolism Animals biosynthesis Cercopithecus aethiops Chagas disease Chagas Disease - parasitology Cloning, Molecular developmental stages Differential expression gene expression regulation Gene Expression Regulation, Enzymologic genes Glycoproteins - genetics Glycoproteins - metabolism Glycosyl-transferase Glycosyltransferases - genetics Glycosyltransferases - metabolism Golgi apparatus Golgi Apparatus - metabolism Infectivity Life Cycle Stages Life Sciences Microbiology and Parasitology mucins Neuraminidase - genetics Neuraminidase - metabolism O-glycosylation pathogenesis pathogenicity Rabbits serine threonine Trypanosoma cruzi Trypanosoma cruzi - enzymology Trypanosoma cruzi - genetics Trypanosoma cruzi - pathogenicity Uridine Diphosphate - metabolism Vero Cells - parasitology
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