Plasmid vector-linked maturation of natural killer cells is coupled to antigen-dependent natural killer cell activation during DNA-based immunization in mice

Plasmid DNA vaccines serve in a wide array of applications ranging from prophylactic vaccines to potential therapeutic tools against infectious diseases and cancer. In this study, we have analyzed the mechanisms underlying the activation of natural killer (NK) cells and their potential role in adapt...

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Veröffentlicht in:Journal of virology 2011-07, Vol.85 (19)
Hauptverfasser: Zhu, Ren, Mancini-Bourgine, Maryline, Zhang, Xiao Ming, Bayard, Florence, Deng, Qiang, Michel, Marie-Louise
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Sprache:eng
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