The Zinc Finger of NEMO Is a Functional Ubiquitin-binding Domain

NEMO (NF-κB essential modulator) is a regulatory protein essential to the canonical NF-κB signaling pathway, notably involved in immune and inflammatory responses, apoptosis, and oncogenesis. Here, we report that the zinc finger (ZF) motif, located in the regulatory C-terminal half of NEMO, forms a...

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Veröffentlicht in:	The Journal of biological chemistry 2009-01, Vol.284 (5), p.2902-2907
Hauptverfasser:	Cordier, Florence, Grubisha, Olivera, Traincard, François, Véron, Michel, Delepierre, Muriel, Agou, Fabrice
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Binding Sites Biochemistry, Molecular Biology Blotting, Western Cell Line Genetic Complementation Test Humans Immunoprecipitation Jurkat Cells Life Sciences Models, Molecular Nuclear Magnetic Resonance, Biomolecular Sequence Homology, Amino Acid Structural Biology Ubiquitin - chemistry Ubiquitin - metabolism Zinc Fingers
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