Oxytocin receptor agonist reduces perinatal brain damage by targeting microglia

Prematurity and fetal growth restriction (FGR) are frequent conditions associated with adverse neurocognitive outcomes. We have previously identified early deregulation of genes controlling neuroinflammation as a putative mechanism linking FGR and abnormal trajectory of the developing brain. While t...

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Veröffentlicht in:	Glia 2019-02, Vol.67 (2), p.345-359
Hauptverfasser:	Mairesse, Jérôme, Zinni, Manuela, Pansiot, Julien, Hassan‐Abdi, Rahma, Demene, Charlie, Colella, Marina, Charriaut‐Marlangue, Christiane, Rideau Batista Novais, Aline, Tanter, Mickael, Maccari, Stefania, Gressens, Pierre, Vaiman, Daniel, Soussi‐Yanicostas, Nadia, Baud, Olivier
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Brain damage Brain injury Cognition Damage prevention Danio rerio Deregulation Dietary supplements Fetuses Head injuries Inflammation Interleukin 1 Life Sciences Low protein diet Microglia Myelination Neural networks Neurobiology Neuromodulation Neurons and Cognition Neuroprotection Nutrient deficiency Oxytocin perinatal stress Proteins Substantia alba Transcription activation Zebrafish
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