Tocilizumab plus dexamethasone versus dexamethasone in patients with moderate-to-severe COVID-19 pneumonia: A randomised clinical trial from the CORIMUNO-19 study group

Background: In moderate-to-severe COVID-19 pneumonia, dexamethasone (DEX) and tocilizumab (TCZ) reduce the occurrence of death and ventilatory support. We investigated the efficacy and safety of DEX+TCZ in an open randomized clinical trial.Methods: From July 24, 2020, through May 18, 2021, patients...

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Veröffentlicht in:	EClinicalMedicine 2022-04, Vol.46
Hauptverfasser:	Hermine, Olivier, Mariette, Xavier, Porcher, Raphael, Djossou, Felix, Nguyen, Yann, Arlet, Jean-Benoît, Savale, Laurent, Diehl, Jean Luc, Georgin-Lavialle, Sophie, Cadranel, Jacques, Pialoux, Gilles, Lacombe, Karine, Mekinian, Arsène, Gros, Hélène, Lescure, Xavier, Ghosn, Jade, Coupez, Elisabeth, Grapin, Kevin, Rapp, Christophe, Michel, Marc, Lecapitaine, Anne Lise, Michot, Jean Marie, Costedoat-Chalumeau, Nathalie, Nguyen, Liem Binh Luong, Semerano, Luca, Raffi, François, Aguillar, Claire, Rouzaud, Claire, Gottenberg, Jacques Eric, Hansmann, Yves, Bienvenu, Boris, London, Jonathan, Fantchou, Franklin Samou, Ackermann, Felix, Gros, Antoine, Morel, Alexandre, Gambier, Nicolas, Sène, Damien, Mégarbane, Bruno, Azoulay, Elie, Bureau, Serge, Dougados, Maxime, Emmerich, Joseph, Fartoukh, Muriel, Guidet, Bertrand, Humbert, Marc, Mahevas, Mathieu, Pène, Frédéric, Schlemmer, Frédéric, Pourcher-Martinez, Valérie, Tibi, Annick, Baron, Gabriel, Perrodeau, Elodie, Baron, Stéphanie, Steg, Gabriel, Yazdapanah, Yazdan, Simon, Tabassome, Resche-Rigon, Matthieu, Tharaux, Pierre-Louis, Ravaud, Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	Human health and pathology Life Sciences
Online-Zugang:	Volltext
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