Water-Soluble Aza-BODIPYs: Biocompatible Organic Dyes for High Contrast In Vivo NIR-II Imaging

A simple NIR-II emitting water-soluble system has been developed and applied in vitro and in vivo. In vitro, the fluorophore quickly accumulated in 2D and 3D cell cultures and rapidly reached the tumor in rodents, showing high NIR-II contrast for up to 1 week. This very efficient probe possesses all...

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Veröffentlicht in:	Bioconjugate chemistry 2020-04, Vol.31 (4), p.1088-1092
Hauptverfasser:	Godard, Amélie, Kalot, Ghadir, Pliquett, Jacques, Busser, Benoit, Le Guével, Xavier, Wegner, K. David, Resch-Genger, Ute, Rousselin, Yoann, Coll, Jean-Luc, Denat, Franck, Bodio, Ewen, Goze, Christine, Sancey, Lucie
Format:	Artikel
Sprache:	eng
Schlagworte:	Aza Compounds - chemistry Biocompatibility Bioengineering Boron Compounds - chemistry Cell Line, Tumor Coloring Agents - chemistry Humans Infrared Rays Life Sciences Optical Imaging - methods Water - chemistry
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