Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates

In Parkinson's disease, synucleinopathy is hypothesized to spread from the enteric nervous system, via the vagus nerve, to the CNS. Here, we compare, in baboon monkeys, the pathological consequences of either intrastriatal or enteric injection of α-synuclein-containing Lewy body extracts from p...

Ausführliche Beschreibung