Compartmentalized Antimicrobial Defenses in Response to Flagellin

Motility is often a pathogenicity determinant of bacteria targeting mucosal tissues. Flagella constitute the machinery that propels bacteria into appropriate niches. Besides motility, the structural component, flagellin, which forms the flagella, targets Toll-like receptor 5 (TLR5) to activate innat...

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Veröffentlicht in:	Trends in microbiology (Regular ed.) 2018-05, Vol.26 (5), p.423-435
Hauptverfasser:	Vijayan, Aneesh, Rumbo, Martin, Carnoy, Christophe, Sirard, Jean-Claude
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive Immunity Anti-Infective Agents - metabolism Anti-Infective Agents - pharmacology Antiinfectives and antibacterials Antimicrobial agents Bacteria Bacteria - immunology Bacteria - pathogenicity Cells Dendritic cells Dendritic Cells - immunology Dendritic structure Epithelial cells Epithelial Cells - immunology Epithelium Flagella Flagellin Flagellin - immunology Helper cells Human health and pathology Immune system Immunity Immunity, Innate Infectious diseases Innate immunity Interleukin-22 Interleukins - metabolism Life Sciences Lymphocytes Lymphocytes - immunology Lymphoid cells Molecular chains Motility Mucosa Pathogenicity Pathogens Proteins Stimulation Tissues TLR5 protein Toll-Like Receptor 5 - metabolism Toll-like receptors
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