Oil composition of high-fat diet affects metabolic inflammation differently in connection with endotoxin receptors in mice

Low-grade inflammation observed in obesity is a risk factor for cardiovascular disease. Recent studies revealed that this would be linked to gut-derived endotoxemia during fat digestion in high-fat diets, but nothing is known about the effect of lipid composition. The study was designed to test the...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2012-02, Vol.302 (3), p.E374-E386
Hauptverfasser:	Laugerette, Fabienne, Furet, Jean-Pierre, Debard, Cyrille, Daira, Patricia, Loizon, Emmanuelle, Géloën, Alain, Soulage, Christophe O, Simonet, Claire, Lefils-Lacourtablaise, Jennifer, Bernoud-Hubac, Nathalie, Bodennec, Jacques, Peretti, Noël, Vidal, Hubert, Michalski, Marie-Caroline
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Acute-Phase Proteins Adipose Tissue, White Adipose Tissue, White - immunology Adipose Tissue, White - metabolism Animals Antigens, CD14 Biological Markers Biomarkers - blood Biomarkers - metabolism Canola Oil Carrier Proteins Carrier Proteins - blood Cytokines Cytokines - blood Cytokines - metabolism Diet Diet, High-Fat Diet, High-Fat - adverse effects Fatty Acids, Monounsaturated Fatty Acids, Nonesterified Fatty Acids, Nonesterified - adverse effects Fatty Acids, Nonesterified - blood Food and Nutrition Gram-Negative Bacteria Gram-Negative Bacteria - immunology Gram-Negative Bacteria - isolation & purification Gram-Positive Bacteria Gram-Positive Bacteria - immunology Gram-Positive Bacteria - isolation & purification Intestines Intestines - immunology Intestines - microbiology Intestines - pathology Life Sciences Lipopolysaccharide Receptors - blood Lipopolysaccharide Receptors - metabolism Male Membrane Glycoproteins Membrane Glycoproteins - blood Metabolic Diseases Metabolic Diseases - etiology Metabolic Diseases - immunology Metabolic Diseases - metabolism Metabolic Diseases - microbiology Metabolism Mice Mice, Inbred C57BL Obesity Palm Oil Plant Oils Plant Oils - adverse effects Random Allocation Receptors, Immunologic Receptors, Immunologic - metabolism Risk factors Rodents Sunflower Oil Toll-Like Receptor 4 Toll-Like Receptor 4 - metabolism
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