Farnesoid x receptor deficiency improves glucose homeostasis in mouse models of obesity: FXR-deficiency improves glucose metabolism in obesity

OBJECTIVE Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through different signaling pathways. The nuclear BA receptor farnesoid X receptor (FXR) regulates pathways in BA, lipid, glucose, and energy metabolism, which become dysregulated in obesity. However, the role o...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2011-07, Vol.60 (7), p.1861-71
Hauptverfasser:	Prawitt, Janne, Abdelkarim, Mouaadh, Stroeve, Johanna H. M., Popescu, Iuliana, Duez, Helene, Velagapudi, Vidya R., Dumont, Julie, Bouchaert, Emmanuel, van Dijk, Theo H., Lucas, Anthony, Dorchies, Emilie, Daoudi, Mehdi, Lestavel, Sophie, Gonzalez, Frank J., Oresic, Matej, Cariou, Bertrand, Kuipers, Folkert, Caron, Sandrine, Staels, Bart
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry, Molecular Biology Life Sciences
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!