Effects of preexisting microdamage, collagen cross-links, degree of mineralization, age, and architecture on compressive mechanical properties of elderly human vertebral trabecular bone

Previous studies have shown that the mechanical properties of trabecular bone are determined by bone volume fraction (BV/TV) and microarchitecture. The purpose of this study was to explore other possible determinants of the mechanical properties of vertebral trabecular bone, namely collagen cross‐li...

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Veröffentlicht in:	Journal of orthopaedic research 2011-04, Vol.29 (4), p.481-488
Hauptverfasser:	Follet, Helene, Viguet-Carrin, Stéphanie, Burt-Pichat, Brigitte, Dépalle, Baptiste, Bala, Yohann, Gineyts, Evelyne, Munoz, Francoise, Arlot, Monique, Boivin, Georges, Chapurlat, Roland D., Delmas, Pierre D., Bouxsein, Mary L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Amino Acids Amino Acids - metabolism Arginine Arginine - analogs & derivatives Arginine - metabolism Biological Markers Biomarkers - metabolism bone strength Calcification, Physiologic Calcification, Physiologic - physiology Collagen Collagen - metabolism collagen cross-links Compressive Strength Cross-Linking Reagents Cross-Linking Reagents - metabolism Engineering Sciences Female Humans Life Sciences Lumbar Vertebrae Lumbar Vertebrae - metabolism Lumbar Vertebrae - pathology Lysine Lysine - analogs & derivatives Lysine - metabolism Male Mechanics Mechanics of materials microarchitecture microdamage Middle Aged mineralization Physics Santé publique et épidémiologie Stress, Mechanical vertebral trabecular bone Weight-Bearing
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