Intravenous Administration of 99mTc-HMPAO-Labeled Human Mesenchymal Stem Cells after Stroke: In Vivo Imaging and Biodistribution

Human mesenchymal stem cells (hMSC) are a promising source for cell therapy after stroke. To deliver these cells, an IV injection appears safer than a local graft. We aimed to assess the whole-body biodistribution of IV-injected 99mTc-HMPAO-labeled hMSC in normal rats (n = 9) and following a right m...

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Veröffentlicht in:	Cell transplantation 2009-01, Vol.18 (12), p.1369-1379
Hauptverfasser:	Detante, Olivier, Moisan, Anaïck, Dimastromatteo, Julien, Richard, Marie-Jeanne, Riou, Laurent, Grillon, Emmanuelle, Barbier, Emmanuel, Desruet, Marie-Dominique, De Fraipont, Florence, Segebarth, Christoph, Jaillard, Assia, Hommel, Marc, Ghezzi, Catherine, Remy, Chantal
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioengineering Humans Injections, Intravenous Life Sciences Magnetic Resonance Imaging Mesenchymal Stem Cell Transplantation Mesenchymal Stem Cells Mesenchymal Stromal Cells - cytology Other Radiopharmaceuticals Radiopharmaceuticals - administration & dosage Rats Rats, Sprague-Dawley Stroke Stroke - pathology Stroke - therapy Technetium Tc 99m Exametazime Technetium Tc 99m Exametazime - administration & dosage Tissue Distribution Whole-Body Counting
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