Endothelial cell apoptosis in severe drug-induced bullous eruptions

Summary Background Toxic epidermal necrolysis (TEN) and Stevens–Johnson syndrome (SJS) are characterized by extensive keratinocyte apoptosis mediated by cytotoxic proteins. Similar features have been found in another severe dysimmune syndrome, allogeneic acute graft‐versus‐host disease, where endot...

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Veröffentlicht in:	British journal of dermatology (1951) 2009-12, Vol.161 (6), p.1371-1375
Hauptverfasser:	Verneuil, L., Ratajczak, P., Allabert, C., Leboeuf, C., Comoz, F., Janin, A., Ameisen, J.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens, CD31 Apoptosis blood vessel Cancer endothelial cell Endothelial Cells Endothelial Cells - metabolism Epidermal Necrolysis, Toxic Female Humans Immunohistochemistry Life Sciences Male Middle Aged Platelet Endothelial Cell Adhesion Molecule-1 - metabolism severe drug-induced bullous eruption Skin Skin - blood supply Skin - metabolism Stevens-Johnson Syndrome Stevens-Johnson Syndrome - metabolism Stevens-Johnson Syndrome - pathology Young Adult
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