Pharmacokinetics of Mycophenolic Acid Administered 3 Times Daily after Hematopoietic Stem Cell Transplantation with Reduced-Intensity Regimen

Mycophenolate mofetil (MMF) is an immunosuppressive drug used as a prophylactic agent to prevent acute graft-versus-host disease (aGVHD) after hematopoietic stem cell transplantation (HSCT). After reduced-intensity conditioning (RIC) regimen, administration of MMF orally 3 times a day (tid) seems to...

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Veröffentlicht in:	Biology of blood and marrow transplantation 2009-09, Vol.15 (9), p.1134-1139
Hauptverfasser:	Royer, Bernard, Larosa, Fabrice, Legrand, Faezeh, Gerritsen-van Schieveen, Pauline, Bérard, Michel, Kantelip, Jean-Pierre, Deconinck, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Drug Administration Schedule Female Graft vs Host Disease Graft vs Host Disease - prevention & control GVHD Hematology, Oncology and Palliative Medicine Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cell Transplantation - methods Humans Immunology Immunosuppressive Agents Immunosuppressive Agents - adverse effects Immunosuppressive Agents - pharmacokinetics Life Sciences Male Middle Aged Mycophenolate mofetil Mycophenolic Acid Mycophenolic Acid - administration & dosage Mycophenolic Acid - adverse effects Mycophenolic Acid - pharmacokinetics Pharmacokinetics Prospective Studies Reduced-intensity hematopoietic cell transplantation Young Adult
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