Ribosome-translocon complex mediates calcium leakage from endoplasmic reticulum stores

Under resting conditions, the endoplasmic reticulum (ER) intraluminal free calcium concentration ([Ca(2+)](ER)) reflects a balance between active uptake by Ca(2+)-ATPases and passive efflux via 'leak channels'. Despite their physiological importance and ubiquitous leak pathway mechanism, v...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cell science 2004-08, Vol.117 (Pt 18), p.4135-4142
Hauptverfasser:	Van Coppenolle, Fabien, Vanden Abeele, Fabien, Slomianny, Christian, Flourakis, Matthieu, Hesketh, John, Dewailly, Etienne, Prevarskaya, Natalia
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium Calcium - metabolism Calcium Channels Calcium Channels - drug effects Calcium Channels - metabolism Calcium Signaling Calcium Signaling - drug effects Calcium Signaling - physiology Calcium-Transporting ATPases Calcium-Transporting ATPases - antagonists & inhibitors Calcium-Transporting ATPases - metabolism Cancer Endoplasmic Reticulum Endoplasmic Reticulum - drug effects Endoplasmic Reticulum - metabolism Endoplasmic Reticulum - ultrastructure Enzyme Inhibitors Enzyme Inhibitors - pharmacology Fura-2 Heparin Heparin - pharmacology Humans Intracellular Membranes Intracellular Membranes - metabolism Intracellular Membranes - ultrastructure Life Sciences Macromolecular Substances Macromolecular Substances - metabolism Microscopy, Electron, Transmission Protein Synthesis Inhi Protein Synthesis Inhibitors - pharmacology Protein Transport - physiology Puromycin - pharmacology Ribosomes - metabolism Ribosomes - ultrastructure Ryanodine - pharmacology Tumor Cells, Cultured
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!