CDK1-cyclin B1 mediates the inhibition of proliferation induced by omega-3 fatty acids in MDA-MB-231 breast cancer cells

Long-chain omega-3 polyunsaturated fatty acids are thought to inhibit the development of breast cancer. We investigated the effects of docosahexaenoic and eicosapentaenoic acids on the proliferation of MDA-MB-231 human mammary epithelial cells. Both docosahexaenoic and eicosapentaenoic acids decreas...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2006-02, Vol.38 (2), p.196-208
Hauptverfasser:	Barascu, Aurélia, Besson, Pierre, Le Floch, Olivier, Bougnoux, Philippe, Jourdan, Marie-Lise
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - metabolism Apoptosis - physiology Breast neoplasms Breast Neoplasms - metabolism Cancer CDC2 Protein Kinase - genetics CDC2 Protein Kinase - metabolism CDK1-cyclin B1 Cell Cycle - physiology Cell Line, Tumor Cell Proliferation Cyclin B - genetics Cyclin B - metabolism Cyclin B1 Docosahexaenoic acid Fatty Acids, Omega-3 - chemistry Fatty Acids, Omega-3 - metabolism Fatty Acids, Omega-3 - pharmacology Female G2/M phases Humans Life Sciences Phospholipids - chemistry
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