Prediction of the metabolic clearance of benzophenone-2, and its interaction with isoeugenol and coumarin using cryopreserved human hepatocytes in primary culture

Benzophenone-2 (BP2) is widely used as a UV screen in both industrial products and cosmetic formulations, where it is frequently found associated with fragrance compounds, such as isoeugenol and coumarin. BP2 is now recognized as an endocrine disruptor, but to date, no information has been reported...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Food and chemical toxicology 2016-04, Vol.90, p.55-63
Hauptverfasser:	de Sousa, Georges, Teng, Sophie, Salle-Siri, Romain, Pery, Alexandre, Rahmani, Roger
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzophenones - pharmacokinetics Cells, Cultured Coumarins - pharmacokinetics Drug Interactions Environmental chemical Eugenol - analogs & derivatives Eugenol - pharmacokinetics Hepatocytes - metabolism Human hepatocytes Humans Life Sciences Metabolic interaction Metabolism Molecular Structure Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!