Analysis of PBPK Models for Risk Characterization

: Adoption of a Bayesian framework for risk characterization permits the seamless integration of different kinds of information available in order to choose and parameterize risk models. It also becomes easy to disentangle uncertainty from variability, through hierarchical statistical modeling. Appr...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 1999-01, Vol.895 (1), p.317-337
1. Verfasser:	BOIS, FRÉDÉRIC YVES
Format:	Artikel
Sprache:	eng
Schlagworte:	Bayes Theorem Environmental Exposure Environmental Pollutants - adverse effects Environmental Pollutants - pharmacokinetics Environmental Sciences Humans Life Sciences Markov Chains Methylene Chloride - adverse effects Methylene Chloride - pharmacokinetics Monte Carlo Method Pharmacokinetics Risk Assessment Sensitivity and Specificity Tetrachloroethylene - adverse effects Tetrachloroethylene - pharmacokinetics Toxicology
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