Characterization of testicular expression of P450 17alpha-hydroxylase, 17,20-lyase in zebrafish and its perturbation by the pharmaceutical fungicide clotrimazole

The aim of the present study was to characterize P450 17alpha-hydroxylase/17,20-lyase (cyp17a1) expression in zebrafish and to assess the effect of the pharmaceutical clotrimazole, a known inhibitor of various cytochrome P450 enzyme activities, on testicular gene and protein expression of this enzym...

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Veröffentlicht in:	General and comparative endocrinology 2011, Vol.174 (3), p.309-317
Hauptverfasser:	Hinfray, Nathalie, Baudiffier, Damien, Leal, Marcello C., Porcher, Jean-Marc, Ait-Aissa, Selim, Le Gac, Florence, Schulz, Rüdiger, Brion, François
Format:	Artikel
Sprache:	eng
Schlagworte:	Ecotoxicology Environmental Sciences Life Sciences Toxicology
Online-Zugang:	Volltext
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