Development of a single ion irradiation system at CENBG for applications in radiation biology

A single event facility is currently under development at CENBG for applications in radiation biology. The aim is to induce the response of living cells by hitting selected individual specimens or specific sub-cellular compartments with an exact number of light ions. In order to avoid the constructi...

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Veröffentlicht in:Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms Beam interactions with materials and atoms, 2001-07, Vol.181 (1), p.104-109
Hauptverfasser: Moretto, Ph, Michelet, C, Balana, A, Barberet, Ph, Przybylowicz, W.J, Slabbert, J.P, Prozesky, V.M, Pineda, C.A, Brut, G, Laurent, G, Lhoste, F
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container_issue 1
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container_title Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms
container_volume 181
creator Moretto, Ph
Michelet, C
Balana, A
Barberet, Ph
Przybylowicz, W.J
Slabbert, J.P
Prozesky, V.M
Pineda, C.A
Brut, G
Laurent, G
Lhoste, F
description A single event facility is currently under development at CENBG for applications in radiation biology. The aim is to induce the response of living cells by hitting selected individual specimens or specific sub-cellular compartments with an exact number of light ions. In order to avoid the construction of a complete beam line, it was decided to adapt the existing microprobe system. The line has been equipped with a removable final irradiation stage constituting a versatile system working on demand either in external beam mode or classical analysis under vacuum. The beam blanking is ensured by particle detectors which have been specifically designed to control MeV proton or alpha beams in a single event mode. This paper presents the overall experimental setup and first in-air experimental tests.
doi_str_mv 10.1016/S0168-583X(01)00624-3
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source Elsevier ScienceDirect Journals
subjects Biological Physics
Cell
Cells
External beam
Ionising radiation
Ions
Microbeam
Particle detectors
Physics
Proton beams
title Development of a single ion irradiation system at CENBG for applications in radiation biology
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