Determination of metallic ion transfer from an implanted prosthesis by the PIXE method

Prostheses can release some metallic elements to the surrounding tissues, particularly when they are not covered with a biomaterial layer and when an unsealing process happens. We try to measure major and trace elements in these tissues with an experimentally sensitive method. Proton-induced X-ray e...

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Veröffentlicht in:Biological trace element research 1999-12, Vol.71-72 (1), p.595-601
Hauptverfasser: Oudadesse, H, Irigaray, J L, Brun, V, Terver, S, Vanneuville, G
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container_issue 1
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container_title Biological trace element research
container_volume 71-72
creator Oudadesse, H
Irigaray, J L
Brun, V
Terver, S
Vanneuville, G
description Prostheses can release some metallic elements to the surrounding tissues, particularly when they are not covered with a biomaterial layer and when an unsealing process happens. We try to measure major and trace elements in these tissues with an experimentally sensitive method. Proton-induced X-ray emission is used to detect about 10 elements in tissue. Tissues are calcinated and deposited in a thin layer before irradiation. Results are obtained in a standard and samples from three patients. We observe contamination by Ti, Cr, Ni, and Zn in the tissues. Correlations are to be studied between these atomic transfers and prosthesis in the patient.
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source MEDLINE; SpringerLink Journals - AutoHoldings
subjects Biological Physics
Biomaterials
Biomedical materials
Chromium
Contamination
Emission
Hip Prosthesis
Ionizing radiation
Ions
Irradiation
Knee Prosthesis
Metallography
Metals
Metals - analysis
Physics
Prostheses
Prosthetics
Spectrometry, X-Ray Emission
Surgical implants
Tissue
Tissues
Titanium
Trace elements
Zinc
title Determination of metallic ion transfer from an implanted prosthesis by the PIXE method
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