Short-term uptake of microcystin-LR by Coregonus lavaretus: GST activity and genotoxicity

In the present study, juvenile whitefish weighing 2 g were exposed by force-feeding to two ecologically relevant doses (0.05 and 0.5 μg per fish) of microcystin-LR (MC-LR). Then over 96 h the MC uptake in fish liver and muscle was measured, as the activity of the detoxification enzyme glutathione S-...

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Veröffentlicht in:	Ecotoxicology (London) 2012-10, Vol.21 (7), p.1788-1796
Hauptverfasser:	Sotton, Benoît, Devaux, Alain, Givaudan, Nicolas, Guillard, Jean, Domaizon, Isabelle, Bony, Sylvie, Anneville, Orlane
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioassays Biodiversity and Ecology Detoxification DNA Damage Earth and Environmental Science Ecology Ecotoxicology Environment Environmental Management Environmental Sciences Enzymes Erythrocytes - drug effects Fish Fishes Genotoxicity Glutathione transferase Glutathione Transferase - metabolism Liver Liver - enzymology Microcystins Microcystins - metabolism Microcystins - pharmacokinetics Microcystins - toxicity Muscles Muscles - metabolism Mutagenicity Tests Organs Oxidative Stress Salmonidae - metabolism Strands Toxins Uptakes
Online-Zugang:	Volltext
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