Dual role for prostaglandin D2 in intestinal epithelial homeostasis

Prostaglandin D2 (PGD2) and derivatives are lipid mediators involved in the control of the intestinal epithelial barrier homeostasis. Their involvement in the pathophysiology of chronic inflammatory bowel disease (IBD) is still debated. Several results highlight the duality of PGD2 as an anti- or pr...

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Veröffentlicht in:	M.S. Médecine sciences 2015-06, Vol.31 (6-7), p.617-621
Hauptverfasser:	Le Loupp, Anne-Gaelle, Bach-Ngohou, Kalyane, Bettan, Armel, Denis, Marc, Masson, Damien
Format:	Artikel
Sprache:	eng ; fre
Schlagworte:	Animals Epithelial Cells Epithelial Cells - physiology Homeostasis Homeostasis - physiology Human health and pathology Humans Inflammatory Bowel Diseases Inflammatory Bowel Diseases - etiology Inflammatory Bowel Diseases - pathology Intestinal Mucosa Intestinal Mucosa - physiology Life Sciences Lipids Lipids - pharmacology Paracrine Communication Prostaglandin D2 Prostaglandin D2 - physiology
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