Neoadjuvant or perioperative therapy for melanoma metastasis in clinical practice: an international survey

[...]question remains of whether the adoption of these still largely unapproved regimens for locoregional melanoma metastases into routine clinical practice is justified. [...]melanoma experts nominated by the Melanoma World Society (MWS) and the European Association of Dermato-Oncology (EADO) were...

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Veröffentlicht in:The lancet oncology 2025-01, Vol.26 (1), p.12-14
Hauptverfasser: Hauschild, Axel, Garbe, Claus, Ascierto, Paolo Antonio, Demidov, Lev, Dreno, Brigitte, Dummer, Reinhard, Eggermont, Alexander, Forsea, Ana-Maria, Gebhardt, Christoffer, Gershenwald, Jeffrey E, Hamid, Omid, Hoeller, Christoph, Kandolf, Lidija, Kaufmann, Roland, Kirkwood, John M, Lebbé, Celeste, Long, Georgina V, Malvehy, Josep, Martin-Algarra, Salvador, McArthur, Grant, Neyns, Bart, Richtig, Erika, Robert, Caroline, Schadendorf, Dirk, Scolyer, Richard, Sondak, Vernon K, Wainstein, Alberto, Weichenthal, Michael, Nuti, Paolo
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container_issue 1
container_start_page 12
container_title The lancet oncology
container_volume 26
creator Hauschild, Axel
Garbe, Claus
Ascierto, Paolo Antonio
Demidov, Lev
Dreno, Brigitte
Dummer, Reinhard
Eggermont, Alexander
Forsea, Ana-Maria
Gebhardt, Christoffer
Gershenwald, Jeffrey E
Hamid, Omid
Hoeller, Christoph
Kandolf, Lidija
Kaufmann, Roland
Kirkwood, John M
Lebbé, Celeste
Long, Georgina V
Malvehy, Josep
Martin-Algarra, Salvador
McArthur, Grant
Neyns, Bart
Richtig, Erika
Robert, Caroline
Schadendorf, Dirk
Scolyer, Richard
Sondak, Vernon K
Wainstein, Alberto
Weichenthal, Michael
Nuti, Paolo
description [...]question remains of whether the adoption of these still largely unapproved regimens for locoregional melanoma metastases into routine clinical practice is justified. [...]melanoma experts nominated by the Melanoma World Society (MWS) and the European Association of Dermato-Oncology (EADO) were surveyed about their opinions and experiences regarding the use of these new therapies for melanoma with locoregional metastasis. [...]the question of which schedule should be introduced first into practice was also answered in favour of the SWOG S1801 schedule (56 [54%] of 104 respondents vs 11 [10%] of 104 respondents for the NADINA or OpACINneo schedule). [...]regarding the approval of neoadjuvant therapies in their countries, 86 (83%) of 104 experts expected the SWOG 1801 regimen to be approved and reimbursed in the next 3 years, while only 52 (50%) of 104 experts foresaw the same for the NADINA or OpACINneo regimen. [...]all experts consider both therapies to be safe enough for patients with resectable locoregional disease (AJCC stage III disease).
doi_str_mv 10.1016/S1470-2045(24)00627-2
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source ScienceDirect Journals (5 years ago - present)
subjects Cancer therapies
Clinical medicine
Committees
FDA approval
Immunotherapy
Life Sciences
Melanoma
Metastases
Metastasis
Oncology
Participation
Polls & surveys
Reimbursement
Roles
Scandals
Schedules
Skin cancer
Surgery
title Neoadjuvant or perioperative therapy for melanoma metastasis in clinical practice: an international survey
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