Chemical ribonucleases. 2. Design and hydrolytic activity of the ribonuclease mimics on the basis of diazabicyclo[2.2.2]octane with a differing number of positive charges

A procedure was proposed allowing one to synthesize RNA mimics on the basis of conjugates of diazabicyclo[2.2.2]octane with imidazole bearing a varying number of positive charges (nDm series, where n is the number of positive charges at neutral pH, m is the code of an imidazole-containing fragment o...

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Veröffentlicht in:Russian journal of bioorganic chemistry 2000-09, Vol.26 (9), p.679-685
Hauptverfasser: Zenkova, Marina A., Vlassov, A. V., Konevets, D. A., Silnikov, V. N., Giegé, Richard, Vlassov, V. V.
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Sprache:rus
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