PAPγ associates with PAXT nuclear exosome to control the abundance of PROMPT ncRNAs

Pervasive transcription of the human genome generates an abundance of RNAs that must be processed and degraded. The nuclear RNA exosome is the main RNA degradation machinery in the nucleus. However, nuclear exosome must be recruited to its substrates by targeting complexes, such as NEXT or PAXT. By...

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Veröffentlicht in:	Nature communications 2023-10, Vol.14 (1)
Hauptverfasser:	Contreras, Xavier, Depierre, David, Akkawi, Charbel, Srbic, Marina, Helsmoortel, Marion, Nogaret, Maguelone, Lehars, Matthieu, Salifou, Kader, Heurteau, Alexandre, Cuvier, Olivier, Kiernan, Rosemary
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences
Online-Zugang:	Volltext
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