Anti-SARS-CoV-2 serology based on ancestral RBD antigens does not correlate with the presence of neutralizing antibodies against Omicron variants

Neutralizing antibody titers and binding antibody levels are considered correlates of protection against severe SARS-CoV-2 infection. The clinical utility of serology should be reevaluated in light of the emergence of escape variants, as commercial antibody-binding assays have not been adapted to th...

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Veröffentlicht in:Microbiology spectrum 2024-11, Vol.2024, p.e0156824
Hauptverfasser: Dépéry, Léa, Bally, Isabelle, Amen, Axelle, Némoz, Benjamin, Buisson, Marlyse, Grossi, Laurence, Truffot, Aurélie, Germi, Raphaële, Guilligay, Delphine, Veloso, Mélanie, Vilotitch, Antoine, Epaulard, Olivier, Morand, Patrice, Weissenhorn, Winfried, Poignard, Pascal, Lupo, Julien
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Sprache:eng
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