Behavioral consequences of dopamine deficiency in the Drosophila central nervous system

The neuromodulatory function of dopamine (DA) is an inherent feature of nervous systems of all animals. To learn more about the function of neural DA in Drosophila, we generated mutant flies that lack tyrosine hydroxylase, and thus DA biosynthesis, selectively in the nervous system. We found that DA...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2011-01, Vol.108 (2), p.834-839
Hauptverfasser:	Riemensperger, Thomas, Isabel, Guillaume, Coulom, Hélène, Neuser, Kirsa, Seugnet, Laurent, Kume, Kazuhiko, Iché-Torres, Magali, Cassar, Marlène, Strauss, Roland, Preat, Thomas, Hirsh, Jay, Birman, Serge, Nash, Howard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal behavior Animals Behavior, Animal Biological Sciences Brain Brain - metabolism Central Nervous System - physiology Cognitive science Dopamine Dopamine - deficiency Dopamine - physiology Dopaminergic neurons Drosophila Drosophila - physiology Frameshift Mutation Homozygote Insects Levodopa - chemistry Memory Memory interference Movement Mutation Nervous system Neurons Neuroscience Neurotransmitter Agents - metabolism Neurotransmitters Odors Phototaxis Proteins Smell Sugars Time Factors Tyrosine 3-Monooxygenase - genetics Walking
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