Synergistic effect of Gemcitabin-loaded metal organic frameworks nanoparticles with particle therapy

[Display omitted] •Gemcitabin-loaded nanoMOFs enhance tumor control and minimize treatment toxicity.•NanoMOFs boost particle therapy efficacy in both normoxic and hypoxic conditions.•Particle therapy offers precise targeting and better efficacy than conventional radiotherapy.•NanoMOFs efficiently de...

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Veröffentlicht in:	International journal of pharmaceutics 2024-11, Vol.665, p.124721, Article 124721
Hauptverfasser:	Maury, Pauline, Hirayama, Ryoichi, Li, Xue, Mahou, Pierre, Schanne-Klein, Marie-Claire, Lacombe, Sandrine, Gref, Ruxandra, Porcel, Erika
Format:	Artikel
Sprache:	eng
Schlagworte:	3D cell model Bioengineering Cancer Drug delivery Hypoxia Life Sciences MOFs Nanoparticles Nuclear medicine Particle therapy Pharmaceutical sciences Pharmacology Radiations
Online-Zugang:	Volltext
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