Surface modification of extracellular vesicles with polyoxazolines to enhance their plasma stability and tumor accumulation

Extracellular vesicles (EVs) are future promising therapeutics, but their instability in vivo after administration remains an important barrier to their further development. Many groups evaluated EV surface modification strategies to add a targeting group with the aim of controlling EV biodistributi...

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Veröffentlicht in:Biomaterials 2025-02, Vol.313, p.122748, Article 122748
Hauptverfasser: Simon, L., Constanzo, J., Terraza-Aguirre, C., Ibn Elfekih, Z., Berthelot, J., Benkhaled, B.T., Haute, T., Pednekar, K., Clark, K., Emerson, S.J., Atis, S., Benedetti, C., Langlois, S., Marquant, A., Prakash, J., Wang, A., Devoisselle, J.M., Montier, T., Djouad, F., Pouget, J.P., Lapinte, V., Morille, Marie
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Sprache:eng
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