Computational detection of antigen-specific B cell receptors following immunization

B cell receptors (BCRs) play a crucial role in recognizing and fighting foreign antigens. High-throughput sequencing enables in-depth sampling of the BCRs repertoire after immunization. However, only a minor fraction of BCRs actively participate in any given infection. To what extent can we accurate...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2024-08, Vol.121 (35), p.e2401058121
Hauptverfasser:	Abbate, Maria Francesca, Dupic, Thomas, Vigne, Emmanuelle, Shahsavarian, Melody A, Walczak, Aleksandra M, Mora, Thierry
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens B-Lymphocytes - immunology Complementarity Complementarity Determining Regions - genetics Complementarity Determining Regions - immunology Complementarity-determining region 3 Computational Biology - methods Computer applications COVID-19 - immunology COVID-19 - prevention & control COVID-19 - virology Drug development High-Throughput Nucleotide Sequencing Humans Immunization Immunization - methods Influenza Vaccines - immunology Influenza, Human - immunology Influenza, Human - prevention & control Life Sciences Next-generation sequencing Precision medicine Public health Receptors Receptors, Antigen, B-Cell - genetics Receptors, Antigen, B-Cell - immunology SARS-CoV-2 - immunology Severe acute respiratory syndrome coronavirus 2 Statistical analysis Vaccination Vaccine development Vaccines
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!