Expedient synthesis of trifunctional oligoethyleneglycol-amine linkers and their use in the preparation of PEG-based branched platforms

We designed a convergent synthesis pathway that provides access to trifunctional oligoethyleneglycol-amine (OEG-amine) linkers. By applying the reductive coupling of a primary azide to bifunctional OEG-azide precursors, the corresponding symmetrical dialkylamine bearing two homo-functional end chain...

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Veröffentlicht in:	Organic & biomolecular chemistry 2018-11, Vol.16 (44), p.8579-8584
Hauptverfasser:	Ursuegui, Sylvain, Schneider, Jérémy P, Imbs, Claire, Lauvoisard, Florian, Dudek, Marta, Mosser, Michel, Wagner, Alain
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical materials Chemical Sciences Coupling Intermediates NMR Nuclear magnetic resonance Organic chemistry Perturbation Synthesis
Online-Zugang:	Volltext
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