Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding

Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding

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Veröffentlicht in:Journal of medicinal chemistry 2021-12, Vol.65 (2), p.1552-1566
Hauptverfasser: Schneider, Melanie, Delfosse, Vanessa, Gelin, Muriel, Grimaldi, Marina, Granell, Meritxell, Heriaud, Laurène, Pons, Jean-Luc, Cohen Gonsaud, Martin, Balaguer, Patrick, Bourguet, William, Labesse, Gilles
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container_issue 2
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container_title Journal of medicinal chemistry
container_volume 65
creator Schneider, Melanie
Delfosse, Vanessa
Gelin, Muriel
Grimaldi, Marina
Granell, Meritxell
Heriaud, Laurène
Pons, Jean-Luc
Cohen Gonsaud, Martin
Balaguer, Patrick
Bourguet, William
Labesse, Gilles
description
doi_str_mv 10.1021/acs.jmedchem.1c01354
format Article
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subjects Life Sciences
title Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding
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