Is Chikungunya Virus Infection an Independent Risk Factor for 2-Year Mortality in Older Afro-Caribbean Subjects?

Purpose: The aim of this study was to investigate whether Chikungunya virus infection (CVI) was an independent risk factor for 2-year mortality in Afro-Caribbean subjects aged 65 years or older. Patients and methods: A retrospective cohort study was performed from January 2014 to December 2016 in the University Hospital of Martinique. Subjects aged >= 65 years admitted to the hospital were included. Baseline characteristics and concurrent manifestations at admission were collected. Subjects were followed up by phone for 2 years. Results: A total of 687 old Afro-Caribbean subjects (80.4 +/- 8.0 years) were included: 467 positive for CVI (Chik+) and 220 negative for CVI (Chik-). During the follow-up, 180 (26.2%) died. The proportion of deaths was higher among Chik- (40.9%) than among Chik+ subjects (21.6%) (p= 65 years or older, Chik+ subjects had significantly higher survival rates than Chik- ones.