Azithromycin disrupts apicoplast biogenesis in replicating and dormant liver stages of the relapsing malaria parasites Plasmodium vivax and Plasmodium cynomolgi

•A major obstacle to Plasmodium vivax eradication is its ability to cause relapse by the activation of hypnozoites.•The use of 8-aminoquinolines to kill hypnozoites is restricted by potential toxicity.•The apicoplast is the site of metabolic functions crucial to the survival of the malaria parasite....

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