Synthesis of linear chitosan-block-dextran copolysaccharides with dihydrazide and dioxyamine linkers

Dihydrazide (ADH) and dioxyamine (PDHA) were assessed for their efficacy in coupling chitosan and dextran via their reducing ends. Initially, the end-functionalization of the individual polysaccharide blocks was investigated. Under non-reducing conditions, chitosan with a 2,5-anhydro-D-mannose unit...

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Veröffentlicht in:	Carbohydrate polymers 2024-12, Vol.345, p.122576, Article 122576
Hauptverfasser:	Courtecuisse, Elise, Bourasseau, Sylvain, Christensen, Bjørn E., Schatz, Christophe
Format:	Artikel
Sprache:	eng
Schlagworte:	Block copolymer Chemical Sciences Chitosan Conjugate Dextran Hydrazone hydrazones hydrogen hydrolysis molecular weight nanoparticles neutralization Oxime Polymers
Online-Zugang:	Volltext
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