Modulation of endothelial permeability by 1-O-alkylglycerols

ABSTRACT Regulation of endothelial barrier function often occurs through signalling involving phospholipase C activation which produces diacylglycerol (DAG), a lipidic second messenger activator of protein kinase C (PKC). Therefore, modification of lipidic composition of endothelial cell membranes m...

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Veröffentlicht in:	Acta physiologica Scandinavica 2002-12, Vol.176 (4), p.263-268
Hauptverfasser:	Marigny, K., Pedrono, F., Martin-Chouly, C. A. E., Youmine, H., Saiag, B., Legrand, A. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	1-O-alkylglycerol Albumins - metabolism Animals Aorta - cytology Biochemistry Biochemistry, Molecular Biology Biological and medical sciences Blood vessels and receptors Calcimycin - pharmacology Cell Membrane Permeability - drug effects Cell Membrane Permeability - physiology Cells, Cultured Coloring Agents - metabolism Diglycerides - metabolism endothelium Endothelium, Vascular - drug effects Endothelium, Vascular - metabolism etherlipids Food and Nutrition Fundamental and applied biological sciences. Psychology Glycerol - analogs & derivatives Glycerol - pharmacology Life Sciences permeability Phospholipids - metabolism protein kinase C Protein Kinase C - antagonists & inhibitors Tetradecanoylphorbol Acetate - pharmacology Tetrazolium Salts - metabolism Thiazoles - metabolism Vertebrates: cardiovascular system
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