The actin-spectrin submembrane scaffold restricts endocytosis along proximal axons

Clathrin-mediated endocytosis has characteristic features in neuronal dendrites and presynapses, but how membrane proteins are internalized along the axon shaft remains unclear. We focused on clathrin-coated structures and endocytosis along the axon initial segment (AIS) and their relationship to th...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 2024-08, Vol.385 (6711), p.eado2032
Hauptverfasser:	Wernert, Florian, Moparthi, Satish Babu, Pelletier, Florence, Lainé, Jeanne, Simons, Eline, Moulay, Gilles, Rueda, Fanny, Jullien, Nicolas, Benkhelifa-Ziyyat, Sofia, Papandréou, Marie-Jeanne, Leterrier, Christophe, Vassilopoulos, Stéphane
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actin Cytoskeleton - metabolism Actins - metabolism Animals Ankyrins Axonal plasticity Axonal transport Axons Axons - metabolism Cell body Cell interactions Cell Membrane - metabolism Cells, Cultured Cellular Biology Clathrin Clathrin - metabolism Clathrin-Coated Vesicles - metabolism Cleavage Coated pits Coated Pits, Cell-Membrane - metabolism Cycle ratio Drug delivery Electron microscopy Endocytosis Exclusion zones Glutamate receptors HEK293 Cells Hippocampus Humans Life Sciences Light microscopy Membrane proteins Membranes Microscopy N-Methyl-D-aspartic acid receptors Neurobiology Neuronal Plasticity Neurons Neurons - metabolism Neurons and Cognition Optical microscopy Pits Plastic properties Plasticity Protein transport Proteins Rats Scaffolds Segments Spectrin Spectrin - metabolism Stability Stimulation Subcellular Processes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!