Targeted Isolation of Antiviral Labdane Diterpenes from the Bark of Neo-uvaria foetida (Annonaceae) using LC-MS/MS-Based Molecular Networking

In the search of new inhibitors for human coronavirus (HCoV), we screened extracts of endemic Annonaceae plants on an assay using a cellular model of Huh-7 cells infected with the human alphacoronavirus HCoV-229E. The EtOAc bark extract of the rare Southeast Asian plant Neo-uvaria foetida exhibited...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2024-08, Vol.87 (8), p.1941-1951
Hauptverfasser:	Sukumaran, S. Yaallini, Herrscher, Charline, Rasol, Nurulfazlina Edayah, Othman, Muhamad Aqmal, Liew, Sook Yee, Ismail, Nor Hadiani, Séron, Karin, Litaudon, Marc, Awang, Khalijah, El Kalamouni, Chaker, Apel, Cécile, Zahari, Azeana
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical Sciences
Online-Zugang:	Volltext
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