The molecular determinants of microglial developmental dynamics

Microglia constitute the largest population of parenchymal macrophages in the brain and are considered a unique subset of central nervous system glial cells owing to their extra-embryonic origins in the yolk sac. During development, microglial progenitors readily proliferate and eventually colonize...

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Veröffentlicht in:	Nature reviews. Neuroscience 2024-06, Vol.25 (6), p.414-427
Hauptverfasser:	Barry-Carroll, Liam, Gomez-Nicola, Diego
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378/2571/219 631/378/2596/1953 Animal Genetics and Genomics Animals Behavioral Sciences Biological Techniques Biomedical and Life Sciences Biomedicine Brain - cytology Brain - growth & development Brain - metabolism Cell Differentiation - physiology Central nervous system Colonization Coronary vessels Electron microscopes Embryogenesis Glial cells Humans Life Sciences Liver Macrophages Microglia Microglia - metabolism Microglia - physiology Neurobiology Neurons and Cognition Neurosciences Review Article Yolk sac
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